1-Bromo-2-nitrobenzene → 7-Methoxy-3-(2-nitrophenyl)-1,2-dihydronaphthalene

HRID 2423621ノート

反応式

HRID 2423621 の反応式
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9].C([Sn](CCCC)(CCCC)C1C=CC=CC=1[N+]([O-])=O)CCC.FC(F)(F)S(O[C:39]1[CH2:48][CH2:47][C:46]2[C:41](=[CH:42][CH:43]=[C:44]([O:49][CH3:50])[CH:45]=2)[CH:40]=1)(=O)=O>>[CH3:50][O:49][C:44]1[CH:45]=[C:46]2[C:41]([CH:40]=[C:39]([C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=3[N+:8]([O-:10])=[O:9])[CH2:48][CH2:47]2)=[CH:42][CH:43]=1

参加物

4

反応物 3

HCID 113411-Bromo-2-nitrobenzeneHCID 11338886Stannane, tributyl(2-nitrophenyl)-HCID 153302566-Methoxy-3,4-dihydronaphthalen-2-yl trifluoromethanesulfonate

生成物 1

HCID 230871487-Methoxy-3-(2-nitrophenyl)-1,2-dihydronaphthalene

実験手順

Synthesized from 1-bromo-2-nitrobenzene according to an analogous synthetic method to Preparation Example 76, tributyl(2-nitrophenyl)tin (7.3 g) and 6-methoxy-3,4-dihydronaphthalen-2-yl trifluoromethanesulfonate (2.2 g) were used according to an analogous synthetic method to Preparation Example 77 to provide the title compound (1.5 g).

後処理

  1. customwere used according to an analogous synthetic method to Preparation Example 77

出典と根拠

ORDレコード
ord-a5a0af87a7b44dd7b1fe1ae80765a1a5
出典データセット
uspto-grants-2011_06
特許番号
US07960412B2

反応ノート

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