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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 242373Generated: October 30, 2026

Chloromethyl Methyl Ether → Imidazole-4-carboxylic acid, 1-methoxymethyl-, ethyl ester

https://huagongshe.com/reaction/242373

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloromethyl Methyl EtherHCID 7864—
ReactantHCID 178469898HCID 178469898—
ProductImidazole-4-carboxylic acid, 1-methoxymethyl-, ethyl esterHCID 542529—

Reaction Steps

In analogy to Step (1) of Example 1, but using ethyl imidazole-4-carboxylate (26.3 g) and chloromethylmethylether (21.2 mL), the title compound (17.2 g) was afforded.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08653126B2
Source datasetuspto-grants-2014_02
ORD IDord-5b6bf02830fc4e699c8bff05c1794303
Source noteuspto-grants-2014_02