HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23087471, compound → HCID 66626414, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23087471 | HCID 23087471 | — |
| Reactant | HCID 66626037 | HCID 66626037 | — |
| Product | HCID 66626414 | HCID 66626414 | 90.6% |
Reaction Steps
Synthesized from {4-{ethyl[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]carbamoyl}phenoxy}acetic acid and heptamethyleneimine according to an analogous synthetic method to Example 378, 4-(2-azocan-1-yl-2-oxoethoxy)-N-ethyl-N-[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]benzamide (262 mg) was used according to an analogous synthetic method to Example 337 to provide [4-(2-azocan-1-ylethoxy)benzyl]ethyl[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amine (226 mg). Synthesized from this compound (218 mg) according to an analogous synthetic method to Example 111, the title compound (168 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960412B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-ac8c6a4b932a4b099ea6d43260228bb3 |
| Source note | uspto-grants-2011_06 |