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HRID2424355

反应详情

EQUATION

反应方程式

HRID 2424355 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1ncccc1C(F)(F)F
HCID13233844

3-(Trifluoromethyl)pyridine-2-carboxylic acid

C7H4F3NO2

结构：CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(N)ccc2F)CCO1
HCID67234727

未命名化合物

PRODUCTS

生成物

1
结构：C[C@@]1(c2cc(NC(=O)c3ncccc3C(F)(F)F)ccc2F)CCOC(N)=N1
HCID53241350

未命名化合物

PROCEDURE

实验过程

The coupling of [(S)-4-(5-amino-2-fluoro-phenyl)-4-methyl-5,6-dihydro-4H-[1,3]oxazin-2-yl]-carbamic acid tert-butyl ester from experiment F1 (R3=Me) and 3-trifluoromethyl-pyridine-2-carboxylic acid followed by deprotection using procedure H yielded the title compound. MS (ESI): m/z=397.0 [M+H]+.