HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 25206093, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 86626635 | HCID 86626635 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 25206093 | HCID 25206093 | — |
Reaction Steps
The compound prepared in example 8 (260 mg, 0.62 mmol) was dissolved in a mixture of 1 mL TFA and 4 mL CH2Cl2 and stirred for 30 min. The solvent was evaporated and the crude product was purified by a short silica gel column (using CH2Cl2-MeOH 98:2 as eluent). Yield: 180 mg (85.6%) Rf=0.38 (CH2Cl2-MeOH 9:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964603B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-74a077dc059e4cad86cc48aeec788ef5 |
| Source note | uspto-grants-2011_06 |