huagongshe.com
HRID242458

反应详情

EQUATION

反应方程式

HRID 242458 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)N
HCID6385

tert-Butylamine

C4H11N

结构：CNC(=O)[C@@H](NC(=O)n1nc(-c2cc(F)c(F)cc2F)c2c1CCN(C)C2)C(C)(C)C
HCID46863441

未命名化合物

结构：CC(C)(C)OC(=O)N1CCc2[nH]nc(-c3ccc(F)c(F)c3)c2C1
HCID59345327

未命名化合物

PRODUCTS

生成物

1
结构：CN1CCc2c(c(-c3ccc(F)c(F)c3)nn2C(=O)NC(C)(C)C)C1
HCID46862473

未命名化合物

PROCEDURE

实验过程

Compound 46 was prepared according to the procedure described for the synthesis of compound 37 by replacing intermediate 19 with intermediate 15, and replacing tert-leucine methylamide with tert-butylamine. 1H NMR (CDCl3) δ 7.47-7.52 (m, 1H), 7.21-7.31 (m, 2H), 4.06 (s, 2H), 3.43 (t, J=6.1 Hz, 2H), 3.20 (t, J=6.1 Hz, 2H0, 2.75 (3H), 1.48 (s, 9H). LCMS (+ESI) m/z=349.2 [M+H]+.