HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamide → 5-Amino-1-(4,4-difluorocyclohexyl)-1h-pyrazole-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamide | HCID 12151703 | — |
| Reactant | 5-Amino-1-(4,4-difluorocyclohexyl)-1h-pyrazole-4-carbonitrile | HCID 58416683 | — |
| Product | 5-Amino-1-(4,4-difluorocyclohexyl)-1h-pyrazole-4-carboxamide | HCID 57556247 | — |
Reaction Steps
Following the procedure for the preparation of 5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamide but substituting 5-amino-1-(4,4-difluorocyclohexyl)-1H-pyrazole-4-carbonitrile provided the title compound. 400 MHz 1H NMR (CD3OD) δ 8.01 (s, 1H), 4.19 (m, 1H), 2.22-1.90 (m, 8H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964607B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-f4dc4744a05f4deb8d31d5edca11d1ec |
| Source note | uspto-grants-2011_06 |