HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamide → 5-amino-1-(2,2,2-trifluoroethyl)-1H-pyrazole-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamide | HCID 12151703 | — |
| Reactant | 5-Amino-1-(2,2,2-trifluoroethyl)-1H-pyrazole-4-carbonitrile | HCID 53418333 | — |
| Product | 5-amino-1-(2,2,2-trifluoroethyl)-1H-pyrazole-4-carboxamide | HCID 57556210 | — |
Reaction Steps
Following the procedure for the preparation of 5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamide but substituting 5-amino-1-(2,2,2-trifluoroethyl)-1H-pyrazole-4-carbonitrile provided the tile compound. 400 MHz 1H NMR (DMSO) δ 7.75 (s, 1H), 7.30 (brs, 1H), 6.78 (brs, 1H) 6.58 (m, 2H), 4.88 (m, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964607B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-d24fdc6547d24a4697d83ea09d18151e |
| Source note | uspto-grants-2011_06 |