HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamide → 5-amino-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamide | HCID 12151703 | — |
| Reactant | HCID 17773354 | HCID 17773354 | — |
| Product | 5-amino-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxamide | HCID 57556276 | — |
Reaction Steps
Following the procedure for the preparation of 5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamide but substituting 5-amino-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carbonitrile provided the title compound. 400 MHz 1H NMR (CD3OD) δ 4.20 (m, 1H), 4.05 (m, 2H), 3.50 (m, 2H), 2.18 (s, 3H), 2.09 (m, 2H), 1.77 (m, 2H). MS: (M+H m/z 225.0).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964607B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-ad5b9bba4f014e0c98096261dd569207 |
| Source note | uspto-grants-2011_06 |