Benzylamine → HCID 67245096, compound

Participants

Reaction Steps

A methanol (1 ml) solution of benzylamine (5.9 g) and (3S,5S)-5-methyl-1-oxaspiro[2.5]octane (3.5 g) were heated in a microwave (100 W) for 30 minutes at 100° C., then concentrated in vacuo and purified by flash column chromatography (SiO2, 20% ethyl acetate/iso-hexane as eluent) to afford the subtitle compound as a colourless oil (4.5 g).

Provenance & Evidence