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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2424866Generated: November 2, 2026

6-Chloromethyl-2-methylpyridinium chloride → 4-[1-(6-Methyl-pyridin-2-ylmethyl)-2-methyl-1H-imidazol-4-ylethynyl]-2-chloro-pyridine

https://huagongshe.com/reaction/2424866

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloromethyl-2-methylpyridinium chlorideHCID 76545—
ReactantHCID 178418879HCID 178418879—
Product4-[1-(6-Methyl-pyridin-2-ylmethyl)-2-methyl-1H-imidazol-4-ylethynyl]-2-chloro-pyridineHCID 11771646—

Reaction Steps

The title compound, MS: m/e=323.2 (M+H+), was prepared in accordance with the general method of example 1 from 2-chloro-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 2-chloromethyl-6-methyl-pyridine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964620B2
Source datasetuspto-grants-2011_06
ORD IDord-d3fe0f7d066f4b4ca1be1c25855988d0
Source noteuspto-grants-2011_06