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HRID242506

反应详情

EQUATION

反应方程式

HRID 242506 的结构方程式

REACTANTS

反应物

2
结构：Cc1nnc(CN)o1
HCID14442192

1-(5-Methyl-1,3,4-oxadiazol-2-yl)methanamine

C4H7N3O

结构：CC(C)(C)[C@H](NC(=O)n1nc(-c2ccc(F)c(F)c2)c2c1CCOC2)C(=O)NCCC#N
HCID46862252

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nnc(CNC(=O)[C@@H](NC(=O)n2nc(-c3ccc(F)c(F)c3)c3c2CCOC3)C(C)(C)C)o1
HCID46862361

未命名化合物

PROCEDURE

实验过程

Compound 113 was prepared by the procedure described for the synthesis of compound 104 by replacing 2-cyanoethylamine with 2-aminomethyl-5-methyl-1,3,4-oxadiazole. LCMS (+ESI) m/z=489.3 [M+H]+. 1H NMR (CDCl3) δ 7.90 (d, J=9.3 Hz, 1H), 7.46-7.52 (m, 1H), 7.28-7.32 (m, 1H), 7.19-7.26 (m, 1H), 6.91 (br, 1H), 4.82 (s, 2H), 4.74-4.79 (m, 1H), 4.58-4.63 (m, 1H), 4.28 (d, J=9.3 Hz, 1H), 3.94 (t, J=5.6 Hz, 2H), 3.17 (br, 2H), 2.51 (s, 3H), 1.12 (s, 9H).