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HRID242507

反应详情

EQUATION

反应方程式

HRID 242507 的结构方程式

REACTANTS

反应物

3
结构：NNc1cc(Cl)ccc1F
HCID2773732

(5-chloro-2-fluorophenyl)hydrazine

C6H6ClFN2

结构：CC(C)(C)OC(=O)[C@@H](N)C(C)(C)C
HCID11252445

tert-butyl 3-methyl-L-valinate

C10H21NO2

结构：CNC(=O)[C@@H](NC(=O)c1nn(-c2ccc(F)c(F)c2)c2c1COCC2)C(C)(C)C
HCID46863093

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)[C@@H](NC(=O)c1nn(-c2cc(Cl)ccc2F)c2c1COCC2)C(C)(C)C
HCID58504324

未命名化合物

PROCEDURE

实验过程

This intermediate was prepared according to the procedure escribed for the synthesis of Compound 114 by replacing 3,4-difluorophenylhydrazine with 2-fluoro-5-chlorophenylhydrazine in step 1, and replacing tert-leucine methyl amide with tert-leucine tert-butyl ester in step 3. LC-MS (+ESI) m/z=466.3 [M+H]+.

WORKUP

后处理

  1. customThis intermediate was prepared