Hydrochloric Acid → HCID 67245521, compound

Participants

Reaction Steps

37% hydrochloric acid (2.5 ml) was added to a solution of 2-chloro-4-acetyloxy-5-methoxy-N-acetyl-benzylamine 2b (0.45 g, 1.66 mmol) in abs. ethanol (15 ml) and the mixture was refluxed for 12 hours. The reaction was cooled and the solvent was evaporated under reduced pressure. The residue was recrystallized from dry acetone to afford the title compound as white crystals in quantitative yield.

Provenance & Evidence