Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425152Generated: October 27, 2026

4-(Trifluoromethyl)phenylboronic acid → 4'-Trifluoromethylbiphenyl-3-sulfonic acid (4-hydroxy-butyl)-amide

https://huagongshe.com/reaction/2425152

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)phenylboronic acidHCID 2734389—
Reactant3-Bromo-N-(4-hydroxybutyl)benzene-1-sulfonamideHCID 59728316—
Product4'-Trifluoromethylbiphenyl-3-sulfonic acid (4-hydroxy-butyl)-amideHCID 11523628—

Reaction Steps

Using a method analogous to that described in Example 40, 3-bromophenyl-sulfonic acid-(4-hydroxybutyl)-amide and 4-trifluoromethylphenyl boronic acid were reacted to give the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964643B2
Source datasetuspto-grants-2011_06
ORD IDord-5afacd2ee7ed4dc6b71086edbbdce41d
Source noteuspto-grants-2011_06