HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-1-butanol → 4-Bromo-N-(4-hydroxybutyl)-2-(trifluoromethyl)benzene-1-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-1-butanol | HCID 25868 | — |
| Reactant | 4-Bromo-2-(trifluoromethyl)benzenesulfonyl chloride | HCID 2778608 | — |
| Product | 4-Bromo-N-(4-hydroxybutyl)-2-(trifluoromethyl)benzene-1-sulfonamide | HCID 16094726 | — |
Reaction Steps
Using a method analogous to that described in Example 1, 4-bromo-2-trifluoromethylphenyl sulphonyl chloride was reacted with 4-aminobutanol, and the title compound obtained as a white solid after recrystallisation from ether/petrol. δC (CDCl3, 62.9 MHz): 26.5, 29.4, 43.3, 62.1, 127.3, 131.7, 131.7, 133.1, 135.4 and 137.9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964643B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-eefe41f4c99447af8db116e58c9739a7 |
| Source note | uspto-grants-2011_06 |