4-Chlorobenzoic Acid → HCID 59689166, compound

HRID 2425207Notes

Reaction equation

HRID 2425207 reaction equation
Cl.[NH2:2][CH2:3][C:4]([NH:6][CH:7]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:8]1[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][CH:9]=1)=[O:5].[Cl:24][C:25]1[CH:33]=[CH:32][C:28]([C:29](O)=[O:30])=[CH:27][CH:26]=1>>[Cl:24][C:25]1[CH:33]=[CH:32][C:28]([C:29]([NH:2][CH2:3][C:4](=[O:5])[NH:6][CH:7]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:8]2[CH:13]=[CH:12][C:11]([C:14]([F:15])([F:16])[F:17])=[CH:10][CH:9]=2)=[O:30])=[CH:27][CH:26]=1

Participants

3

Reactant 2

HCID 63184-Chlorobenzoic AcidHCID 67245336HCID 67245336, compound

Product 1

HCID 59689166HCID 59689166, compound

Procedure

Prepared in analogy to example 1.12 from rac-2-amino-N-[phenyl-(4-trifluoromethyl-phenyl)-methyl]-acetamide hydrochloride (example 3.2) and 4-chlorobenzoic acid.

Sources & evidence

ORD record
ord-7600bda3981e4e69bb096264d4482725
Source dataset
uspto-grants-2011_06
Patent number
US07964645B2

Reaction notes

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