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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425237Generated: October 26, 2026

Alanine, N-(4-fluorobenzoyl)- → Rac-4-fluoro-n-((s)-1-{[phenyl-(3-trifluoromethyl-phenyl)-methyl]-carbamoyl}-ethyl)-benzamide

https://huagongshe.com/reaction/2425237

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAlanine, N-(4-fluorobenzoyl)-HCID 732160—
ReactantPhenyl(3-(trifluoromethyl)phenyl)methanamineHCID 21528802—
ProductRac-4-fluoro-n-((s)-1-{[phenyl-(3-trifluoromethyl-phenyl)-methyl]-carbamoyl}-ethyl)-benzamideHCID 59689136—

Reaction Steps

Prepared in analogy to example 1.1 from (S)-2-(4-fluoro-benzoylamino)-propionic acid (CA [214629-12-6]) and rac-C-phenyl-C-(3-trifluoromethyl-phenyl)-methylamine (CA [70428-92-1]).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964645B2
Source datasetuspto-grants-2011_06
ORD IDord-d88a1266772647439d1bf6f475c1bd98
Source noteuspto-grants-2011_06