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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425255Generated: October 28, 2026

5-Methylthiophene-2-carboxylic acid → 5-Methyl-thiophene-2-carboxylic acid ({[bis-(3-fluoro-phenyl)-methyl]-carbamoyl}-methyl)-amide

https://huagongshe.com/reaction/2425255

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Methylthiophene-2-carboxylic acidHCID 74713—
Reactant2-amino-N-[bis-(3-fluoro-phenyl)-methyl]-acetamideHCID 59689153—
Product5-Methyl-thiophene-2-carboxylic acid ({[bis-(3-fluoro-phenyl)-methyl]-carbamoyl}-methyl)-amideHCID 24896775—

Reaction Steps

Prepared in analogy to example 1.12 from 2-amino-N-[bis-(3-fluoro-phenyl)-methyl]-acetamide (example 3.4) and 5-methyl-thiophene-2-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964645B2
Source datasetuspto-grants-2011_06
ORD IDord-e6be05c8605c49079a59a4333f6b8edc
Source noteuspto-grants-2011_06