HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-Amino-N-[(4-chloro-phenyl)-phenyl-methyl]-acetamide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | ({[(4-Chloro-phenyl)-phenyl-methyl]-carbamoyl}-methyl)-carbamic acid tert-butyl ester | HCID 59689146 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 2-Amino-N-[(4-chloro-phenyl)-phenyl-methyl]-acetamide hydrochloride | HCID 67246438 | 100% |
Reaction Steps
6.6 mmol ({[(4-Chloro-phenyl)-phenyl-methyl]-carbamoyl}-methyl)-carbamic acid tert-butyl ester were treated with 30 ml of a saturated solution of hydrogen chloride in diethyl ether. The mixture was stirred at room temperature for 1 hour. Removal of the diethyl ether in the rotatory evaporator yields the title compound as a colorless solid. Yield=100%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964645B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-89b0d6a4a01a4fafb5e7dca0957c0d82 |
| Source note | uspto-grants-2011_06 |