2-Naphthol → Binol

Participants

Reaction Conditions

Reaction Steps

Add 2 g 2-naphthol, 11.4 g FeCl3.6H2O and 100 ml water into a 200 ml beaker and agitate them at 65° C. by water bath; conduct TLC (thin-layer chromatography) track and maintain the reaction for 3 h; filter the solution to get solid 2,2′-dihydroxyl-1,1′-binaphthyl; scrub 2,2′-dihydroxyl-1,1′-binaphthyl with 50 ml water and add the cleaning solution into the filtrate; add 7.5 ml 30% H2O2 dropwise slowly into the filtrate while agitation and agitate the solution continuously for 10 min; add 2 g 2-naphthol and maintain the reaction at 65° C. while agitation; conduct TLC track until the reaction finishes; filter the solution to obtain 2,2′-dihydroxyl-1,1′-binaphthyl. Repeat these steps and obtain results as shown in Table 6. The HPLC analysis results of the reaction product obtained in the 11th time of cycle are: the conversion of 2-naphthol ≧98%, and the yield of 2,2′-dihydroxyl-1,1′-binaphthyl ≦99%.

Provenance & Evidence