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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425397Generated: October 28, 2026

(S)-3-(tert-Butoxycarbonylamino)-1-(4-bromo-5-isoquinolinesulfonyl)pyrrolidine → Hydrochloric Acid

https://huagongshe.com/reaction/2425397

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-3-(tert-Butoxycarbonylamino)-1-(4-bromo-5-isoquinolinesulfonyl)pyrrolidineHCID 67242852—
ReactantHCID 67243206HCID 67243206—
ProductHydrochloric AcidHCID 313—
ProductHCID 178507922HCID 178507922—

Reaction Steps

Intermediate 16 can be used in the method of Example 6-1, Step A instead of Intermediate 1a, then the resultant can be used in the method of Step B in a similar manner, and then the title compound can be obtained as hydrochloride according to the method described in Example 7-1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964613B2
Source datasetuspto-grants-2011_06
ORD IDord-37e3722f7f384abcbd840e8ea13d84bc
Source noteuspto-grants-2011_06