HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl N-(pyrrolidin-3-yl)carbamate → Hydrochloric Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl N-(pyrrolidin-3-yl)carbamate | HCID 2757234 | — |
| Reactant | 4-Bromo-5-isoquinolinesulfonyl chloride | HCID 14580058 | — |
| Reactant | HCID 67243257 | HCID 67243257 | — |
| Product | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 67244881 | HCID 67244881 | — |
Reaction Steps
4-Chloro-5-isoquinolinesulfonyl chloride obtained in Reference Example 7 and 3-(tert-butoxycarbonylaminomethyl)azetidine were used in the method of Example 1, Step A instead of 4-bromo-5-isoquinolinesulfonyl chloride and 3-(tert-butoxycarbonylamino)pyrrolidine, respectively, to prepare 3-[(tert-butoxycarbonylamino)methyl]-1-(4-chloro-5-isoquinolinesulfonyl)azetidine, and then the resultant was used in the method of Example 1, Step B to obtain the title compound as hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964613B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-1cdf5f03de7b4d20af38b591437efc51 |
| Source note | uspto-grants-2011_06 |