HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Hydrochloric Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Furfural | HCID 7362 | — |
| Reactant | tert-Butyl N-(3-oxopropyl)carbamate | HCID 10910051 | — |
| Reactant | HCID 67245570 | HCID 67245570 | — |
| Product | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 67241310 | HCID 67241310 | — |
Reaction Steps
Hydrochloride of the compound obtained in Example 19-2 and 3-(tert-butoxycarbonylamino)propionaldehyde can be used in the method of Example 4-1, Step A instead of hydrochloride of the compound prepared in Example 1-1 and furfural, respectively, to prepare (R)-3-[3-(tert-butoxycarbonylamino)propyl]amino-1-(4-chloro-5-isoquinolinesulfonyl)pyrrolidine, and then the resultant can be used in the method of Example 1, Step B to obtain the title compound as hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964613B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-e25acbc5845f4b8d96f4dd7c12a50308 |
| Source note | uspto-grants-2011_06 |