HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67180429, compound → Methyl 2-(4-(1-aminoethyl)-5-methyl-1H-pyrazol-1-yl)acetate dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67180429 | HCID 67180429 | — |
| Reactant | Methyl 2-(4-acetyl-5-methyl-1H-pyrazol-1-yl)acetate | HCID 67181907 | — |
| Product | Methyl 2-(4-(1-aminoethyl)-5-methyl-1H-pyrazol-1-yl)acetate dihydrochloride | HCID 67181378 | 6.6% |
Reaction Steps
The title compound was prepared in 6.6% yield by the process as described for (R)-1-(1,5-dimethyl-1H-pyrazol-4-yl)ethanamine dihydrochloride (Amine 2) using methyl 2-(4-acetyl-5-methyl-1H-pyrazol-1-yl)acetate (Step A8A) as a starting material. 1H NMR (300 MHz, DMSO-d5) δ 1.48 (3H, d, J=6.0 Hz), 2.22 (3H, s), 3.69 (3H, s), 4.29-4.33 (1H, m), 5.05 (2H, s), 7.59 (1H, s), 8.26 (3H, brs).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964732B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-72e19205a5a14bc5b43cdfcd270bcfd3 |
| Source note | uspto-grants-2011_06 |