Sodium Hydroxide → HCID 20627927, compound

Participants

Reaction Steps

A mixture of methyl 6-tert-butyl-2-naphthoate (Step CA2A)(843 mg, 3.48 mmol) and 2M sodium hydroxide solution (6.96 mmol, 3.48 mmol) in methanol (30 ml) was treated according to the procedure described in step CA1G to furnish the title compound as a white solid (614 mg, 77%). 1H NMR (270 MHz, DMSO-d6): 1.39 (9H, s), 7.70-7.76 (1H, m), 7.90-8.08 (4H, m), 8.55 (1H, br, s), 13.00 (1H, br, s).

Provenance & Evidence