HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Methanesulfonylethyl)piperazine dihydrochloride → HCID 86761343, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Methanesulfonylethyl)piperazine dihydrochloride | HCID 17749885 | — |
| Reactant | HCID 86761342 | HCID 86761342 | — |
| Product | HCID 86761343 | HCID 86761343 | — |
Reaction Steps
[(4S,5R)-2-[4-tert-Butyl-2-(2,2,2-trifluoro-ethoxy)-phenyl]-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazol-1-yl]-[4-(2-methanesulfonyl-ethyl)-piperazin-1-yl]-methanone hydrochloride was prepared from (4S,5R)-2-[4-tert-butyl-2-(2,2,2-trifluoro-ethoxy)-phenyl]-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride (example 12l) and 1-(2-methanesulfonylethyl)piperazine dihydrochloride (example 17) in an analogous manner as described in example 25. LR-MS: 739.4 [(M+H)+]
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07964724B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-8862c74bc2ae4d369d0755d3012fb61d |
| Source note | uspto-grants-2011_06 |