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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425709Generated: October 28, 2026

1-(2-Methanesulfonylethyl)piperazine dihydrochloride → HCID 86761343, compound

https://huagongshe.com/reaction/2425709

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Methanesulfonylethyl)piperazine dihydrochlorideHCID 17749885—
ReactantHCID 86761342HCID 86761342—
ProductHCID 86761343HCID 86761343—

Reaction Steps

[(4S,5R)-2-[4-tert-Butyl-2-(2,2,2-trifluoro-ethoxy)-phenyl]-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazol-1-yl]-[4-(2-methanesulfonyl-ethyl)-piperazin-1-yl]-methanone hydrochloride was prepared from (4S,5R)-2-[4-tert-butyl-2-(2,2,2-trifluoro-ethoxy)-phenyl]-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride (example 12l) and 1-(2-methanesulfonylethyl)piperazine dihydrochloride (example 17) in an analogous manner as described in example 25. LR-MS: 739.4 [(M+H)+]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07964724B2
Source datasetuspto-grants-2011_06
ORD IDord-8862c74bc2ae4d369d0755d3012fb61d
Source noteuspto-grants-2011_06