Hydrochloric Acid → HCID 67246199, compound

Participants

Reaction Steps

tert-Butyl 4-{[4-({[(1-isopropyl-5-methyl-2-oxo-1,2-dihydroquinolin-3-yl)carbonyl]amino}methyl)piperidine-1-yl]methyl}piperidine-1 carboxylate (150 mg, 0.28 mmol, step 1) was dissolved in 10% methanolic hydrogen chloride (20 mL) and the mixture was stirred for 16 h at room temperature. The mixture was concentrated to give yellow oil, which was crystallized from diethyl ether and n-hexane. The solid was collected by filtration to give 110 mg (96%) of the title compound as a pale yellow solid.

Provenance & Evidence