HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Dimethylpyrrolidine → HCID 59341129, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Dimethylpyrrolidine | HCID 96034 | — |
| Reactant | 4-Chloro-5-fluoro-6-(2-pentynyloxy)pyrimidine | HCID 59341120 | — |
| Product | HCID 59341129 | HCID 59341129 | 46.4% |
Reaction Steps
0.2 g of 4-chloro-5-fluoro-6-(2-pentynyloxy)pyrimidine and 0.2 g of 2,5-dimethylpyrrolidine were mixed and left for 13 hours at room temperature. The reaction mixture was subjected to silica gel column chromatography to obtain 0.12 g of 4-(2,5-dimethyl-1-pyrrolidinyl)-5-fluoro-6-(2-pentynyloxy)pyrimidine (hereinafter, referred to as Compound (13)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07968537B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-f8cdef6c1f4a458cb9df7ee6e2669f47 |
| Source note | uspto-grants-2011_06 |