Potassium Hydroxide → HCID 73174863, compound

Participants

Reaction Conditions

Reaction Steps

5-(4-Isopropylpiperazine-1-carbonyl)thiophene-2-carboxylic acid {1-[5-(3,4-dichlorophenyl)-4-hydroxythiophen-3-yl]ethylidene}hydrazide hydrochloride (14 mg, 0.025 mmol) was suspended in methanol (2.7 mL), and 0.1 M potassium hydroxide in methanol (0.24 mL) and methanol (5.4 mL) were added. The suspension was heated at 50° C. and concentrated to dryness under reduced pressure to give the desired product (yield 100%).

Provenance & Evidence