HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425950Generated: October 31, 2026
2-(3,4-Dichlorophenyl)-3-hydroxy-4-(methylcarbonyl)thiophene → HCID 73224738, compound
https://huagongshe.com/reaction/2425950
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-(3,4-Dichlorophenyl)-3-hydroxy-4-(methylcarbonyl)thiophene | HCID 44207288 | — |
| Reactant | 5-(Hydrazinecarbonyl)-N-(pyridin-3-yl)thiophene-2-carboxamide | HCID 57688107 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 73224738 | HCID 73224738 | 94% |
Reaction Steps
28 mg of 2-(3,4-dichlorophenyl)-3-hydroxy-4-methylcarbonylthiophene and 26 mg of 5-hydrazinocarbonylthiophene-2-carboxylic acid 3-pyridylamide were dissolved in 2 mL of dimethyl sulfoxide and heated at 100° C. for 18 hours, and the solvent was evaporated. Recrystallization from chloroform-diethyl ether gave the desired product (yield 94%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07968542B2 |
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| Source dataset | uspto-grants-2011_06 |
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| ORD ID | ord-b24acaeea6b34f8ebf1fbe85654e8a08 |
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| Source note | uspto-grants-2011_06 |
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