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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2425952Generated: October 28, 2026

5-Hydrazinocarbonylthiophene-2-carboxylic acid methyl-2-picolylamide → 5-{1-[5-(4-Trifluoromethylphenyl)-4-hydroxythiophen-3-yl]ethylidenehydrazinocarbonyl}thiophene-2-carboxylic Acid methyl-2-picolylamide

https://huagongshe.com/reaction/2425952

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Hydrazinocarbonylthiophene-2-carboxylic acid methyl-2-picolylamideHCID 57688132—
Reactant1-{4-Hydroxy-5-[4-(trifluoromethyl)phenyl]thiophen-3-yl}ethan-1-oneHCID 60206789—
Product5-{1-[5-(4-Trifluoromethylphenyl)-4-hydroxythiophen-3-yl]ethylidenehydrazinocarbonyl}thiophene-2-carboxylic Acid methyl-2-picolylamideHCID 73224979—

Reaction Steps

Synthesis was carried out in the same manner as in Synthetic Example 7 by using 2-(4-trifluoromethylphenyl)-3-hydroxy-4-methylcarbonylthiophene and 5-hydrazinocarbonylthiophene-2-carboxylic acid methyl-2-picolylamide prepared in Reference Synthetic Example 10.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07968542B2
Source datasetuspto-grants-2011_06
ORD IDord-1a0524ab76a54f60aeaeeb772ad06fe3
Source noteuspto-grants-2011_06