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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2426286Generated: November 1, 2026

Ethyl Acetate → 6-Nitro-2-(2,3-dihydro-1,4-benzodioxine-6-yl)-quinazoline

https://huagongshe.com/reaction/2426286

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl AcetateHCID 8857—
Reactant6-Nitro-2-(1,3-benzodioxole-5-yl)-quinazolineHCID 57863156—
Product6-Nitro-2-(2,3-dihydro-1,4-benzodioxine-6-yl)-quinazolineHCID 5786314270%

Reaction Steps

This compound was synthesized in 70% yield, according to the procedure described in example 1 for the synthesis of 6-nitro-2-(1,3-benzodioxole-5-yl)-quinazoline. C16H11N3O4, MW: 309.28. mp. 263-265° C.; TLC (tol/AcOEt 7/3) Rf=0.80.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07968558B2
Source datasetuspto-grants-2011_06
ORD IDord-e2d2544204e8477196eb619b4ff8ba88
Source noteuspto-grants-2011_06