HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178465557, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 6-Amino-2-(2,3-dihydro-5-benzofuryl)-quinazoline | HCID 57863161 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 178465557 | HCID 178465557 | 65% |
Reaction Steps
A suspension of 6-amino-2-(2,3-dihydro-5-benzofuryl)-quinazoline (1.4 g, 0.0053 mol) in MeCN (50 ml) was satured with HCl at 0° C. and stirred at r.t. for 24 hrs. The precipitated was filtered and triturated with acetone/methanol. The light yellow solid was filtered and dried in vacuum at 40° C. to give the titled compound, 1.3 g, 65% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07968558B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-8339dcabc173453f90ca4090ced228fe |
| Source note | uspto-grants-2011_06 |