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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2426287Generated: November 2, 2026

Hydrochloric Acid → HCID 178465557, compound

https://huagongshe.com/reaction/2426287

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant6-Amino-2-(2,3-dihydro-5-benzofuryl)-quinazolineHCID 57863161—
SolventAcetonitrileHCID 6342—
ProductHCID 178465557HCID 17846555765%

Reaction Steps

A suspension of 6-amino-2-(2,3-dihydro-5-benzofuryl)-quinazoline (1.4 g, 0.0053 mol) in MeCN (50 ml) was satured with HCl at 0° C. and stirred at r.t. for 24 hrs. The precipitated was filtered and triturated with acetone/methanol. The light yellow solid was filtered and dried in vacuum at 40° C. to give the titled compound, 1.3 g, 65% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07968558B2
Source datasetuspto-grants-2011_06
ORD IDord-8339dcabc173453f90ca4090ced228fe
Source noteuspto-grants-2011_06