Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2426510Generated: November 1, 2026

2-(3-methoxy-6-pyridin-4-yl-pyridazin-4-yl)-3-vinyl-1H-indole methanol → 3-Ethyl-2-(3-methoxy-6-pyridin-4-yl-pyridazin-4-yl)-1H-indole

https://huagongshe.com/reaction/2426510

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-methoxy-6-pyridin-4-yl-pyridazin-4-yl)-3-vinyl-1H-indole methanolHCID 86612050—
CatalystPalladiumHCID 23938—
Product3-Ethyl-2-(3-methoxy-6-pyridin-4-yl-pyridazin-4-yl)-1H-indoleHCID 23092455—

Reaction Steps

12 mg Palladium, 10% on charcoal are added to a solution of 70 mg 2-(3-Methoxy-6-pyridin-4-yl-pyridazin-4-yl)-3-vinyl-1H-indole methanol, and the reaction mixture is stirred under an hydrogen atmosphere for 4 hours. The catalyst is removed by filtration and the solvent by evaporation yielding the product which was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07968546B2
Source datasetuspto-grants-2011_06
ORD IDord-0920ab515cd948e28e712d481724a39e
Source noteuspto-grants-2011_06