Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2426613Generated: October 29, 2026

p-Fluoronitrobenzene → tert-butyl [(3R)-1-(4-nitrophenyl)pyrrolidin-3-yl]carbamate

https://huagongshe.com/reaction/2426613

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-FluoronitrobenzeneHCID 9590—
Reactant(3R)-(+)-3-(tert-Butoxycarbonylamino)pyrrolidineHCID 1514397—
Producttert-butyl [(3R)-1-(4-nitrophenyl)pyrrolidin-3-yl]carbamateHCID 86594863—

Reaction Steps

tert-Butyl (R)-pyrrolidin-3-ylcarbamate was reacted with 4-fluoronitro-benzene by method C. This resulted in the product with the molecular weight of 307.35 (C15H21N3O4); MS (ESI): 308 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07968550B2
Source datasetuspto-grants-2011_06
ORD IDord-35258c36fbeb4e8aa71665fef45abb96
Source noteuspto-grants-2011_06