Bromomethylcyclopropane → HCID 21105577, compound

HRID 2426639Notes

Reaction equation

HRID 2426639 reaction equation
[C:1]([CH2:4][NH:5][CH:6]1[CH2:10][CH2:9][N:8]([C:11]2[CH:16]=[CH:15][C:14]([NH:17][C:18](=[O:28])[CH:19]([C:21]3[CH:26]=[CH:25][C:24]([OH:27])=[CH:23][CH:22]=3)[CH3:20])=[CH:13][CH:12]=2)[CH2:7]1)(=[O:3])[CH3:2].Br[CH2:30][CH:31]1[CH2:33][CH2:32]1>>[C:1]([CH2:4][NH:5][CH:6]1[CH2:10][CH2:9][N:8]([C:11]2[CH:12]=[CH:13][C:14]([NH:17][C:18](=[O:28])[CH:19]([C:21]3[CH:26]=[CH:25][C:24]([O:27][CH2:30][CH:31]4[CH2:33][CH2:32]4)=[CH:23][CH:22]=3)[CH3:20])=[CH:15][CH:16]=2)[CH2:7]1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 81503BromomethylcyclopropaneHCID 21105581HCID 21105581, compound

Product 1

HCID 21105577HCID 21105577, compound

Procedure

N-{4-[3-(Acetylmethylamino)pyrrolidin-1-yl]phenyl}-2-(4-hydroxyphenyl)propionamide was reacted with bromomethylcyclopropane by method H. This resulted in the product with the molecular weight of 435.57 (C26H33N3O3); MS(ESI): 436 (M+H+).

Workup

  1. customThis resulted in the product with the molecular weight of 435.57 (C26H33N3O3)

Sources & evidence

ORD record
ord-43c7a1c20d144288bc28c205d53a281f
Source dataset
uspto-grants-2011_06
Patent number
US07968550B2

Reaction notes

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