Iodoethane → HCID 67131035, compound
Reaction equation
[O:1]=[C:2]1[NH:6][C:5]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)([CH2:7][O:8][CH2:9][CH:10]=[CH2:11])[C:4](=[O:18])[N:3]1[C:19]1[CH:26]=[CH:25][C:22]([C:23]#[N:24])=[C:21]([C:27]([F:30])([F:29])[F:28])[CH:20]=1.I[CH2:32][CH3:33]>>[O:1]=[C:2]1[N:6]([CH2:32][CH3:33])[C:5]([C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)([CH2:7][O:8][CH2:9][CH:10]=[CH2:11])[C:4](=[O:18])[N:3]1[C:19]1[CH:26]=[CH:25][C:22]([C:23]#[N:24])=[C:21]([C:27]([F:30])([F:28])[F:29])[CH:20]=1Participants
3
Procedure
The procedure of Example 1, Step 1 applied to 0.23 g of 4-[2,5-dioxo-4-phenyl-4-[(2-propenyloxy)methyl]imidazolidin-1-yl]-2-trifluoromethylbenzonitrile with 0.18 mL of iodoethane provides the desired compound.
Sources & evidence
- ORD record
- ord-c1ca7b3fe7a34d8695f48ef90232ed0f
- Source dataset
- uspto-grants-2011_06
- Patent number
- US07968581B2
Reaction notes
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