Potassium Cyanide → HCID 67131146, compound

HRID 2427156Notes

Reaction equation

HRID 2427156 reaction equation
[C:1]1([C:7](=O)[CH2:8][O:9][CH2:10][CH:11]=[CH2:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C-]#N.[K+].[C:17](=[O:20])([O-])[O-].[NH4+:21].[NH4+:22].[CH2:23]([OH:25])C.O>CCCCCCC.C(OCC)(=O)C.O>[C:1]1([C:7]2([CH2:8][O:9][CH2:10][CH:11]=[CH2:12])[C:23](=[O:25])[NH:22][C:17](=[O:20])[NH:21]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

7

Reactant 4

HCID 9032Potassium CyanideHCID 517111Ammonium CarbonateHCID 13507957HCID 13507957, compoundHCID 19096565Water ethanol

Product 1

HCID 67131146HCID 67131146, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 21899848Ethylacetate heptaneSolvent

Procedure

0.775 g of 1-phenyl-2-(2-propenyloxy)ethanone, 0.575 g of potassium cyanide and 1.6 g of ammonium carbonate are heated to 55° C. for 3 hours in 23 mL of a 50/50 ethanol/water mixture. The reaction mixture is diluted with water and extracted with ethyl acetate. The organic solution is washed with a saturated aqueous sodium chloride solution, then dried over sodium sulphate and evaporated to yield the desired compound.

Workup

  1. extractionextracted with ethyl acetate
  2. washThe organic solution is washed with a saturated aqueous sodium chloride solution
  3. dry with materialdried over sodium sulphate
  4. customevaporated

Sources & evidence

ORD record
ord-c1089cd3799b4dc49b292f6671b02f13
Source dataset
uspto-grants-2011_06
Patent number
US07968581B2

Reaction notes

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