HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Chloro-4-nitro-phenylsulfanyl)-benzothiazole-6-carbonitrile → 2-(4-Amino-2-chloro-phenylsulfanyl)-benzothiazole-6-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Chloro-4-nitro-phenylsulfanyl)-benzothiazole-6-carbonitrile | HCID 22148829 | — |
| Reactant | Tin tetrachloride dihydrate | HCID 85782573 | — |
| Product | 2-(4-Amino-2-chloro-phenylsulfanyl)-benzothiazole-6-carbonitrile | HCID 22148778 | 93% |
Reaction Steps
The title compound was prepared using the method of example 270, starting with 2-(2-chloro-4-nitro-phenylsulfanyl)-benzothiazole-6-carbonitrile (261) (1.6 g, 4.6 mmol), tin chloride dihydrate (Aldrich, 5.21 g, 23.1 mmol). Compound 273 (1.36 g, 93%) was obtained as a yellowish solid. MS (M+H) 318.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07968567B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-83417f075ea643dbbdd15b79a91cf5bb |
| Source note | uspto-grants-2011_06 |