Lithium Hydroxide → HCID 74943869, compound

HRID 2427930Notes

Reaction equation

HRID 2427930 reaction equation
[CH3:1][C:2]([CH3:8])([CH3:7])[C:3](=[N:5][OH:6])[CH3:4].[Li+].[OH-].[CH2:11]1[O:13][CH2:12]1>O>[OH:13][CH2:12][CH2:11][O:6][N:5]=[C:3]([C:2]([CH3:8])([CH3:7])[CH3:1])[CH3:4]

Participants

5

Reactant 3

HCID 3939Lithium HydroxideHCID 6354Ethylene OxideHCID 137609N-(3,3-Dimethylbutan-2-ylidene)hydroxylamine

Product 1

HCID 74943869HCID 74943869, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

400 ml of water, 92 g (0.8 mol) of 3,3-dimethylbutan-2-one oxime and 3.4 g of LiOH were initially charged, and 70 g (1.6 mol) of ethylene oxide were introduced such that the gas was taken up completely. Thereafter, the mixture was stirred at room temperature (RT) for 8-12 hours for the continued reaction. The upper phase was removed, admixed with ethyl acetate and washed with water. The organic phase was concentrated under reduced pressure at 100-200 mbar. Residue: 114-120 g of colorless oil, which corresponds to a yield of 90% yield; b.p. 106° C./35 mbar.

Workup

  1. customfor the continued reaction
  2. customThe upper phase was removed
  3. washwashed with water
  4. concentrationThe organic phase was concentrated under reduced pressure at 100-200 mbar

Sources & evidence

ORD record
ord-01bef4b727d14d56b3db211d3f892815
Source dataset
uspto-grants-2011_06
Patent number
US07968747B2

Reaction notes

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