HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyridinemethanamine → HCID 21737544, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyridinemethanamine | HCID 19509 | — |
| Reactant | Trolox | HCID 40634 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Product | HCID 21737544 | HCID 21737544 | 85.5% |
Reaction Steps
Following the amide coupling procedure described in protocol A, 499 mg 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (1.99 mmol), 370 mg CDI (2.28 mmol) and 324 mg 2-picolylamine (3.0 mmol), produced 579 mg of 6-hydroxy-2,5,7,8-tetramethyl-N-(pyridin-2-ylmethyl)chroman-2-carboxamide as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07968746B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-9766c091ac1849fca293342188ffb091 |
| Source note | uspto-grants-2011_06 |