(5-Fluoro-2-nitrophenyl)pyridin-2-yl-amine → 4-Fluoro-N2-pyridin-2-ylbenzene-1,2-diamine

Participants

Reaction Steps

A mixture of (5-fluoro-2-nitrophenyl)pyridin-2-yl-amine (3.92 g, 17 mmol) in EtOAc (150 mL) was degassed with a stream of nitrogen prior to addition of 10% Pd/C (500 mg) and was stirred at RT under a hydrogen atmosphere for 18 h. The suspension was filtered through a phase separator and the filtrate concentrated in vacuo to afford the title compound as a black solid (3.5 g, quantitative).

Provenance & Evidence