HCID 68157451, compound → HCID 68157931, compound

Participants

Reaction Steps

(5-Fluoro-2-nitrophenyl)pyrimidin-4-ylamine (0.31 g, 1.32 mmol) in IMS was hydrogenated at RT and pressure for 3.5 h using Pd—C (30 mg) as a catalyst. The catalyst was removed by filtration through Celite. The filtrate was concentrated in vacuo to give the title compound as an orange solid, (0.249 g, 92%). LCMS (Method J): RT=0.56 min, [M+H]+=205.16

Provenance & Evidence