Hydrochloric Acid → HCID 68157878, compound

Participants

Reaction Steps

(6-Fluoro-1-phenyl-1H-benzoimidazol-2-ylmethyl)carbamic acid tert-butyl ester (0.265 g, 0.77 mmol) was treated with 4M HCl in dioxan (5 mL) for 45 min at room temperature. The reaction was evaporated to dryness and the residue triturated with diethyl ether to give the title product as a white solid, (226 mg, approx 100%). LCMS (Method B): RT 2.06 min [M+H]+ 241.98

Provenance & Evidence