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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 24328Generated: October 28, 2026

Potassium Hydroxide → 4-(2-carboxyethyl)-2-methyl-1H-pyrrole-3-carboxylic acid

https://huagongshe.com/reaction/24328

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium HydroxideHCID 14797—
Reactant2-Methyl-3-carbethoxy-4-(3-propionic acid)pyrroleHCID 21728744—
SolventEthanolHCID 702—
Product4-(2-carboxyethyl)-2-methyl-1H-pyrrole-3-carboxylic acidHCID 2257104464%

Reaction Steps

4-(2-Carboxyethyl)-3-ethoxycarbonyl-2-methylpyrrole (Bulter, A. R., and George, S. D. (1993) Tetrahedron 49: 7017-7026) was hydrolyzed using potassium hydroxide (KOH) in ethanol (EtOH) to give 4-(2-carboxyethyl)-2-methyl-1H-pyrrole-3-carboxylic acid (64%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06855730B2
Source datasetuspto-grants-2005_02
ORD IDord-0e408daf6e994476bc66956e12dee526
Source noteuspto-grants-2005_02