HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 59442801, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 59442799 | HCID 59442799 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 59442801 | HCID 59442801 | 225% |
Reaction Steps
To a solution of tert-butyl 2-((4-benzylpiperazin-1-yl)methyl)morpholine-4-carboxylate (600 mg) in CH2Cl2 (10 ml) is added trifluoroacetic acid (1.8 ml), and the mixture is stirred over night. The solvent is removed under reduced pressure to give 2-((4-benzylpiperazin-1-yl)methyl)morpholine*3 TFA (990 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08653262B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-bca997268e0d4f43b9c58ab7126a3248 |
| Source note | uspto-grants-2014_02 |