反应详情

温度

50 °C

2-(4-(4-benzylpiperazin-1-yl)cyclohexyl)-N,N-dimethylethanamine (660 mg) is dissolved in ethanol (20 ml). Palladium on carbon (100 mg) is added and the mixture is stirred for 16 hours at 50° C. under an atmosphere of hydrogen (50 psi). The catalyst is removed by filtration and the filtrate concentrated under reduced pressure to give N,N-dimethyl-2-(4-(piperazin-1-yl)cyclohexyl)ethanamine (412 mg). m/z(+) 240 (M+H+).

1. customThe catalyst is removed by filtration
2. concentrationthe filtrate concentrated under reduced pressure