octanedioic acid [4-(3-Nitro-phenyl)-thiazol-2-yl]-amide → octanedioic acid [4-(3-Amino-phenyl)-thiazol-2-yl]-amide

Beteiligte Stoffe

Reaktionsschritte

Compound 21 was prepared using the methodology described for the preparation of compound 18, by substituting compound 14 with compound 20. Yield (0.276 g, 79.8%). 1H NMR (300 MHz, CDCl3) δ 7.21 (1H, t, J=7.7 Hz), 7.07 (1H, d, J=8.2 Hz), 6.99 (2H, s), 6.69 (1H, d, J=7.8 Hz), 2.49 (2H, t, J=7.3 Hz), 2.40 (2H, t, J=7.1 Hz), 1.78 (2H, brs), 1.69 (2H, t, J=6.7 Hz), 1.50-1.35 (4H, m). 13C NMR (75 MHz, CDCl3) δ 179.6, 172.2, 160.8, 149.7, 147.1, 135.0, 130.2, 117.3, 115.6, 113.5, 108.1, 36.7, 34.4, 29.1, 28.9, 25.5, 24.9.

Herkunft & Nachweise