反应详情

Dimethyl 4-fluoro-2-nitrophenylmalonate (5.0 g) was refluxed in 20 ml of 6 N hydrochloric acid for 24 hours. The reaction was cooled and the white solid which formed was collected by vacuum filtration, washed with water and dried to give 3.3 g (87% yield) of 4-fluoro-2-nitrophenylacetic acid.

1. temperatureThe reaction was cooled
2. customthe white solid which formed
3. filtrationwas collected by vacuum filtration
4. washwashed with water
5. customdried